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¹ Gazi Üniversitesi Fen Fakültesi Biyoloji Bölümü, Ankara
² Ankara Üniversitesi Ziraat Fakültesi Bahçe Bitkileri Bölümü, Ankara
³ Hacettepe Üniversitesi Fen Fakültesi Biyoloji Bölümü, Ankara DOI : 10.21566/tbmaed.45530 - Hydrogen peroxide (H₂O₂) and Nitric oxide (NO) are signalling molecules that play an important role in different organisms. Even though intensive research in the past two decades, knowledge about the role of these two molecules interact with each other in abiotic stress tolerance and the relationship with biological processes aren`t completely elucidated yet. In this paper, H₂O₂ and NO cross-talk and possible role in plant responses to abiotic stresses such as drought, salinity, extreme temperatures, UV irradiation and heavy metals at the level of biosynthesis and gene expression and protein activities are investigated in light of recent literature. In addition, the cross-talk between H₂O₂ and NO with other signalling pathways in the regulation of abiotic stress responses in plants is also discussed. Keywords : Abiotic stress, nitric oxide, hydrogen peroxide, signaling